Although most supplements have good safety records, each person’s body will react differently depending on his or her unique physiology as well as on any other medications, herbs, and supplements also being taken. In addition, certain combinations of medications, herbs, and nutrients can potentially cause depletions or interactions. For that reason it is important to check with your health practitioner. Also try Rx Answers, which contains depletion and interaction information for drugs, nutritional supplements, herbs, and foods.